IT IS VITALLY IMPORTANT that parents and the medical team establish and maintain a relationship based on excellent medical care, good communication, and caring. In this partnership, trust is paramount. Doctors rely on parents to make and keep appointments, give the proper medicines at the appropriate times, prepare the child for procedures, and monitor the child for signs of illness or side effects. Parents rely on doctors for medical knowledge, expertise in performing procedures, good judgment, compassion, and clear communication. It is a delicate balance that spans years of trauma and emotional upheaval. A climate of cooperation and respect between the healthcare team and parents allows children to thrive. This chapter explores ways to create and maintain that environment.