Dr. Jeffery Klco is a member of the Crazy 8 team that is studying Small Moledule Degraders for Targeting Transcription Factor Drivers of Childhood Cancer. On the Crazy 8 project, he says "It gives us a lot of flexibility to take chances and risks. And of course, that's really the way that we need to proceed and make progress with pediatric cancer."

Dr. Klco is a physician scientist that received both his MD and PhD at Washington University School of Medicine. He completed his residency in Anatomic Pathology, fellowship in Hematopathology and trained as a post-doctoral fellow under Tim Ley in acute myeloid leukemia (AML) genomics and mouse models, also at Washington University School of Medicine. Dr. Klco is a leader in the St. Jude Pathology Department as the Director of the Division of Hematopathology and Molecular Pathology. He has an independent research program focused on defining the molecular and biological causes of pediatric myeloid tumors. As both a physician and a scientist, Dr. Klco is uniquely positioned to tailor his research in the lab to study what he observes in patients to maximize the impact of his results.