Childhood Cancer

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Investigating the Role of the MYCN Oncogene in Regulating Chemokine Expression in Neuroblastoma

Institution: 
Children’s Hospital of Philadelphia
Researcher(s): 
Mykaela Salvacion
Grant Type: 
POST Program Grants
Year Awarded: 
2023
Type of Childhood Cancer: 
Neuroblastoma
Project Description: 

Mentor Name: John Maris 

 

Understanding the impact of MYCN degradation on chemokine
secretion as a mechanism to induce an immune response and tumor remodeling will inform
drug development efforts about the biological significance of MYCN-targeting compounds.

Co-funded by: 
Northwestern Mutual Foundation