’The interplay between DNA damage and histone mutations in pediatric gliomas’
Institution:
Dana-Farber Cancer InstituteResearcher(s):
Annarah CharlesGrant Type:
POST Program GrantsYear Awarded:
2022Type of Childhood Cancer:
Brain TumorsProject Description:
Mentor Name: Pratiti Bandopadhayay
During my summer internship, I will study how the different effects each histone mutation has on DNA repair. To do this, we will use model systems that the lab has developed to introduce histone mutations into normal cells. I will use a range of molecular biology methods to study the effect of these mutations on normal cells and the subsequent changes in normal cellular processes, including different DNA repair responses.
Co-funded by:
Northwestern Mutual Foundation
