Mechanisms of LGR5 Regulation and Function in Ewing sarcoma Metastasis |
University of Michigan / Elizabeth Lawlor, M.D., Ph.D. |
Innovation Grants |
2014 |
Michigan |
Modeling the Multi-hit Pathogenesis of t(12;21) Associated Pediatric ALL by CRISPR/Cas-mediated Genome Engineering |
Massachusetts General Hospital / Hanno Hock, M.D., Ph.D. |
Innovation Grants |
2014 |
Massachusetts |
Developing Personalized (precision) Medicine Strategies to Optimize Pediatric Brain Tumor Management |
Washington University / David Gutmann, M.D., Ph.D. |
Innovation Grants |
2014 |
Missouri |
Two-pronged Cell Therapy: Engineering T Cells to Redirect Bystander T- and NK-Cells to Pediatric Cancer |
Baylor College of Medicine / Stephen Gottschalk, M.D. |
Innovation Grants |
2014 |
Texas |
Development of AAV Vectors for Efficient Targeting and Elimination of Osteosarcoma Tumor-Initiating Cells |
University of Florida / Steven Ghivizzani, Ph.D. |
Innovation Grants |
2014 |
Florida |
Targeting MYC/MYCN-driven Transcriptional Amplification in Pediatric Cancer |
Dana-Farber Cancer Institute / Rani George, M.D., Ph.D. |
Innovation Grants |
2014 |
Massachusetts |
Converting the Glioblastoma Multiforme Tumor-Associated Macrophage Phenotype |
The Johns Hopkins University School of Medicine / Alan D. Friedman, M.D. |
Innovation Grants |
2014 |
Maryland |
Targeting the Six1/Eya Transcriptional Complex to Inhibit Pediatric Sarcomas |
University of Colorado Denver / Heide Ford, Ph.D. |
Innovation Grants |
2014 |
Colorado |
Mechanisms and Targeted Inhibition of NT5C2 Mutations in Relapsed ALL |
Columbia University / Adolfo A. Ferrando, M.D., Ph.D. |
Innovation Grants |
2014 |
New York |
Exploiting Epigenetic Dependencies of Notch1 for Clinical Benefit |
University of Colorado Denver / Patricia Ernst, Ph.D. |
Innovation Grants |
2014 |
Colorado |