Enhanced Drug Repurposing Screen in DSRCT Enabled by New In Vitro and In Vivo Models Based on CRISPR/Cas9 Genome Engineering |
Memorial Sloan-Kettering Cancer Center / Marc Ladanyi, MD & Maria Jasin, PhD |
Innovation Grants |
2015 |
New York |
High-dimensional Biochemical CyTOF Analysis of Pediatric T cell Leukemias |
University of California San Francisco / Jeroen Roose, PhD |
Innovation Grants |
2015 |
California |
Developing a Novel Tumor Model to Screen for New Therapies for Spinal Ependymoma |
The Johns Hopkins University School of Medicine / Linda Resar, MD & Richard Schlegel, MD, PhD |
Innovation Grants |
2015 |
Maryland |
Integrative Genomic and Immunogenomic Analysis of Neuroblastoma |
University of California at Santa Cruz / David Haussler, PhD |
Innovation Grants |
2015 |
California |
Identifying Epigenetic Mechanisms Impacting Neuroblastoma Genome Stability and Drug Response |
Massachusetts General Hospital / Johnathan Whetstine, PhD |
Innovation Grants |
2015 |
Massachusetts |
Optimizing Bispecific Antibody Therapy for Acute Leukemias |
Fred Hutchinson Cancer Research Center / Roland Walter, MD, PhD & James Olson, MD, PhD |
Innovation Grants |
2015 |
Washington |
Functional Analysis and Therapeutic Targeting of STAG2 Mutations in Ewing sarcoma |
Georgetown University / Todd Waldman, MD, PhD |
Innovation Grants |
2015 |
District of Columbia |
Identifying how Pre-existing Anti-Therapeutic Antibodies (PATA) are Associated with Better Outcome in a Clinical Trial of ADCC-inducing Anti-GD2 mAb |
University of Wisconsin - Madison / Paul Sondel, MD, PhD |
Innovation Grants |
2015 |
Wisconsin |
Antibody Targeted Natural Killer Cell-Derived Extracellular Vesicles for the Treatment of Childhood Acute Lymphoblastic Leukemia and Neuroblastoma |
Children’s Hospital Los Angeles / Robert Seeger, MD & Alan Wayne, MD |
Innovation Grants |
2015 |
California |
Preclinical Development of Atr Inhibitor VE-822, Delivered Systemically in Nanoparticles, for Medulloblastoma Therapy |
University of North Carolina / Timothy Gershon, MD, PhD |
Innovation Grants |
2015 |
North Carolina |