Targeting mechanisms of Siglec15-mediated immune evasion in hematologic malignancies |
Emory University / Christopher Porter, MD |
Innovation Grants |
2019 |
Georgia |
The anti-tumor immune microenvironment in the Sonic Hedgehog subclass of medulloblastoma |
Emory University / Anna Kenney, PhD |
Innovation Grants |
2019 |
Georgia |
Therapeutic Targeting of the Disrupted Metabolic State in DIPG |
University of Michigan / Costas Lyssiotis, PhD & Sriram Venneti, MD/PhD |
Innovation Grants |
2019 |
Michigan |
Norepinephrine Transporter-Targeted Pharmacotherapy of Aggressive Neuroblastoma |
Children’s Hospital of Philadelphia / Michael Chorny, PhD |
Innovation Grants |
2019 |
Pennsylvania |
Targeting microenvironment-induced TGFB signaling to overcome drug resistance in acute lymphoblastic leukemia |
St. Jude Children’s Research Hospital / Charles Mullighan, MD |
Innovation Grants |
2019 |
Tennessee |
Novel Therapy of Heterogeneous B-cell Acute Lymphocytic Leukemia by Targeting Convergent Oncogenic Mediators STATs |
University of Alberta / Hasan Uludag, PhD |
Innovation Grants |
2019 |
Alberta |
Pediatric Osteosarcoma: Identifying the elusive molecular signature and its relationship to this disease |
St. Jude Children’s Research Hospital / Linda Hendershot, PhD |
Innovation Grants |
2019 |
Tennessee |
Saturating CRISPR gene body scans in MLL-rearranged leukemia |
Beckman Research Institute of City of Hope / Chun-Wei Chen, PhD |
Innovation Grants |
2019 |
California |
Role of the macro lncRNA KCNQ1OT1 in embryonal rhabdomyosarcoma tumorigenesis |
Duke University / Corinne Linardic, MD/PhD |
Innovation Grants |
2019 |
North Carolina |
Predicting and Overcoming Resistance to Immunotherapy in Pediatric High-Grade Glioma |
Ann & Robert H. Lurie Children’s Hospital of Chicago / Oren Becher, MD & Robert Wechsler-Reya, PhD |
Innovation Grants |
2019 |
Illinois |